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high-fidelity intraluminal manometry catheter assembly  (POWERLAB INC)

 
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    POWERLAB INC high-fidelity intraluminal manometry catheter assembly
    Effect of miRNA-133a overexpression on basal (A), agonist-induced increase in IAS tone (B), and reversal of the decreased <t>intraluminal</t> pressures of IAS (IASP) by anti-miR-133a (C). A: miR-133a produces significant and concentration-dependent (20 and 60 nM) decreases in the IAS tone (*P < 0.05; n = 4) compared with scrambled miR (control) or another miR-200c. Decrease in IAS tone by 60 nM miR-133a is significantly blocked by 60 nM antagomirs (**P < 0.05; n = 4). B: miR-133a significantly shifts U46619 concentration-response curve (CRC) of increase in the IAS tone toward the right (*P < 0.05; n = 6–8). The latter is blocked by the antagomirs pretreatment so that U46619 CRC in the presence of 60 nM of miR-133a + antimiR is not significantly different from control (P > 0.05; n = 6–8). C: perianal injection of anti-miR-133a significantly (**P < 0.05) rescues the decreased (*P < 0.05) IASP during aging in 26-mo-old rats compared with their corresponding 6-mo-old rats, both in males and females (n = 6 animals, 3 males and 3 females used for each animal group). The rescuing effect was found to be sustained for up to 72 h following the injection of the anti-miR, both in males and females.
    High Fidelity Intraluminal Manometry Catheter Assembly, supplied by POWERLAB INC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/high-fidelity+intraluminal+manometry+catheter+assembly/high+fidelity+intraluminal+manometry+catheter+assembly/pmc05130548-113-5-11
    Average 90 stars, based on 1 article reviews
    high-fidelity intraluminal manometry catheter assembly - by Bioz Stars, 2026-09
    90/100 stars

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    1) Product Images from "Aging-associated changes in microRNA expression profile of internal anal sphincter smooth muscle: Role of microRNA-133a"

    Article Title: Aging-associated changes in microRNA expression profile of internal anal sphincter smooth muscle: Role of microRNA-133a

    Journal: American Journal of Physiology - Gastrointestinal and Liver Physiology

    doi: 10.1152/ajpgi.00290.2016

    Effect of miRNA-133a overexpression on basal (A), agonist-induced increase in IAS tone (B), and reversal of the decreased intraluminal pressures of IAS (IASP) by anti-miR-133a (C). A: miR-133a produces significant and concentration-dependent (20 and 60 nM) decreases in the IAS tone (*P < 0.05; n = 4) compared with scrambled miR (control) or another miR-200c. Decrease in IAS tone by 60 nM miR-133a is significantly blocked by 60 nM antagomirs (**P < 0.05; n = 4). B: miR-133a significantly shifts U46619 concentration-response curve (CRC) of increase in the IAS tone toward the right (*P < 0.05; n = 6–8). The latter is blocked by the antagomirs pretreatment so that U46619 CRC in the presence of 60 nM of miR-133a + antimiR is not significantly different from control (P > 0.05; n = 6–8). C: perianal injection of anti-miR-133a significantly (**P < 0.05) rescues the decreased (*P < 0.05) IASP during aging in 26-mo-old rats compared with their corresponding 6-mo-old rats, both in males and females (n = 6 animals, 3 males and 3 females used for each animal group). The rescuing effect was found to be sustained for up to 72 h following the injection of the anti-miR, both in males and females.
    Figure Legend Snippet: Effect of miRNA-133a overexpression on basal (A), agonist-induced increase in IAS tone (B), and reversal of the decreased intraluminal pressures of IAS (IASP) by anti-miR-133a (C). A: miR-133a produces significant and concentration-dependent (20 and 60 nM) decreases in the IAS tone (*P < 0.05; n = 4) compared with scrambled miR (control) or another miR-200c. Decrease in IAS tone by 60 nM miR-133a is significantly blocked by 60 nM antagomirs (**P < 0.05; n = 4). B: miR-133a significantly shifts U46619 concentration-response curve (CRC) of increase in the IAS tone toward the right (*P < 0.05; n = 6–8). The latter is blocked by the antagomirs pretreatment so that U46619 CRC in the presence of 60 nM of miR-133a + antimiR is not significantly different from control (P > 0.05; n = 6–8). C: perianal injection of anti-miR-133a significantly (**P < 0.05) rescues the decreased (*P < 0.05) IASP during aging in 26-mo-old rats compared with their corresponding 6-mo-old rats, both in males and females (n = 6 animals, 3 males and 3 females used for each animal group). The rescuing effect was found to be sustained for up to 72 h following the injection of the anti-miR, both in males and females.

    Techniques Used: Over Expression, Concentration Assay, Control, Injection



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    high-fidelity intraluminal manometry catheter assembly  (POWERLAB INC)
    90
    POWERLAB INC high-fidelity intraluminal manometry catheter assembly
    Effect of miRNA-133a overexpression on basal (A), agonist-induced increase in IAS tone (B), and reversal of the decreased <t>intraluminal</t> pressures of IAS (IASP) by anti-miR-133a (C). A: miR-133a produces significant and concentration-dependent (20 and 60 nM) decreases in the IAS tone (*P < 0.05; n = 4) compared with scrambled miR (control) or another miR-200c. Decrease in IAS tone by 60 nM miR-133a is significantly blocked by 60 nM antagomirs (**P < 0.05; n = 4). B: miR-133a significantly shifts U46619 concentration-response curve (CRC) of increase in the IAS tone toward the right (*P < 0.05; n = 6–8). The latter is blocked by the antagomirs pretreatment so that U46619 CRC in the presence of 60 nM of miR-133a + antimiR is not significantly different from control (P > 0.05; n = 6–8). C: perianal injection of anti-miR-133a significantly (**P < 0.05) rescues the decreased (*P < 0.05) IASP during aging in 26-mo-old rats compared with their corresponding 6-mo-old rats, both in males and females (n = 6 animals, 3 males and 3 females used for each animal group). The rescuing effect was found to be sustained for up to 72 h following the injection of the anti-miR, both in males and females.
    High Fidelity Intraluminal Manometry Catheter Assembly, supplied by POWERLAB INC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/high-fidelity+intraluminal+manometry+catheter+assembly/high+fidelity+intraluminal+manometry+catheter+assembly/pmc05130548-113-5-11
    Average 90 stars, based on 1 article reviews
    high-fidelity intraluminal manometry catheter assembly - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier

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    Effect of miRNA-133a overexpression on basal (A), agonist-induced increase in IAS tone (B), and reversal of the decreased intraluminal pressures of IAS (IASP) by anti-miR-133a (C). A: miR-133a produces significant and concentration-dependent (20 and 60 nM) decreases in the IAS tone (*P < 0.05; n = 4) compared with scrambled miR (control) or another miR-200c. Decrease in IAS tone by 60 nM miR-133a is significantly blocked by 60 nM antagomirs (**P < 0.05; n = 4). B: miR-133a significantly shifts U46619 concentration-response curve (CRC) of increase in the IAS tone toward the right (*P < 0.05; n = 6–8). The latter is blocked by the antagomirs pretreatment so that U46619 CRC in the presence of 60 nM of miR-133a + antimiR is not significantly different from control (P > 0.05; n = 6–8). C: perianal injection of anti-miR-133a significantly (**P < 0.05) rescues the decreased (*P < 0.05) IASP during aging in 26-mo-old rats compared with their corresponding 6-mo-old rats, both in males and females (n = 6 animals, 3 males and 3 females used for each animal group). The rescuing effect was found to be sustained for up to 72 h following the injection of the anti-miR, both in males and females.

    Journal: American Journal of Physiology - Gastrointestinal and Liver Physiology

    Article Title: Aging-associated changes in microRNA expression profile of internal anal sphincter smooth muscle: Role of microRNA-133a

    doi: 10.1152/ajpgi.00290.2016

    Figure Lengend Snippet: Effect of miRNA-133a overexpression on basal (A), agonist-induced increase in IAS tone (B), and reversal of the decreased intraluminal pressures of IAS (IASP) by anti-miR-133a (C). A: miR-133a produces significant and concentration-dependent (20 and 60 nM) decreases in the IAS tone (*P < 0.05; n = 4) compared with scrambled miR (control) or another miR-200c. Decrease in IAS tone by 60 nM miR-133a is significantly blocked by 60 nM antagomirs (**P < 0.05; n = 4). B: miR-133a significantly shifts U46619 concentration-response curve (CRC) of increase in the IAS tone toward the right (*P < 0.05; n = 6–8). The latter is blocked by the antagomirs pretreatment so that U46619 CRC in the presence of 60 nM of miR-133a + antimiR is not significantly different from control (P > 0.05; n = 6–8). C: perianal injection of anti-miR-133a significantly (**P < 0.05) rescues the decreased (*P < 0.05) IASP during aging in 26-mo-old rats compared with their corresponding 6-mo-old rats, both in males and females (n = 6 animals, 3 males and 3 females used for each animal group). The rescuing effect was found to be sustained for up to 72 h following the injection of the anti-miR, both in males and females.

    Article Snippet: The IASP was measured using high-fidelity intraluminal manometry catheter assembly via PowerLab/8SP recorder and analyzed via the software Chart 4 PowerLab (ADInstruments).

    Techniques: Over Expression, Concentration Assay, Control, Injection